Melanotan I Peptide: The Complete Guide - Uses, Mechanism, Dosing, Safety & Research
Melanotan I (MT-1), scientifically designated [Nle4-D-Phe7]-alpha-MSH and commercially known as afamelanotide (Scenesse), is a synthetic 13-amino acid analog of alpha-melanocyte-stimulating hormone developed at the University of Arizona in the 1980s. It is the only FDA-approved compound in the melanocortin peptide class, approved in 2019 for erythropoietic protoporphyria , a rare and painful photosensitivity disorder , and is also studied for broader UV photoprotection, tanning, and anti-inflammatory applications. This guide covers what MT-1 does, how it works at the receptor level, what the clinical trial data actually shows, dosing context, safety considerations, how it compares to Melanotan II, and its current regulatory status.
