6 Best Peptides for Stretch Marks
Several peptides have built a real following for stretch mark improvement, with GHK-Cu consistently emerging as the most widely used and most evidence-supported option, followed by Matrixyl and a handful of others that people reach for depending on how fresh the marks are and what approach they prefer. No peptide has been validated in a large, published, peer-reviewed human trial specifically for striae distensae as of 2026, so the honest picture is one of strong mechanistic rationale, promising indirect evidence, and a substantial body of user-reported results rather than definitive clinical proof. This guide covers six peptides people actually use or discuss for stretch marks, ordered by how prominently each appears in research and real-world use, not as a ranking of one compound over another.